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Successfully Prescribing MAOIs for Depression

Psychiatric Times

2,3 MAOIs inhibit MAO in the brain, thereby increasing the intracellular concentrations of serotonin (5HT), norepinephrine (NE), and dopamine (DA), resulting in an absolute increase in extracellular synaptic monoamine concentrations of these 3 major neurotransmitters linked to mood and anxiety disorders. 2015; 35(4):433-449.

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The 6 Steps to Catalyze CBT and DBT With Young Patients

Psychiatric Times

Guilford Press; 2015. Cognitive-Behavioral Treatment of Borderline Personality Disorder. Principles of cognitive-behavioral therapy for anxiety disorders in children. J Am Acad Child Adolesc Psychiatry. 2015;54(7):527-531. Friedberg RD, McClure JM. Persons JB. The Case Formulation Approach to Cognitive-Behavior Therapy.

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Postpartum Depression with Comorbid Anxiety: Optimizing Treatment

MGH Center for Women's Mental Health

Validated instruments such as the Edinburgh Postnatal Depression Scale (EPDS) can identify anxiety symptoms; however, screening can be supplemented with anxiety-specific screening instruments , such as the Generalized Anxiety Disorder 7-item scale (GAD-7) and the Perinatal Anxiety Screening Scale (PASS).

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Psychotherapy and Psychosomatics: End of an Era for Independent Journals? An Interview With Giovanni Fava

Mad in America

One thing is that if you give an antidepressant, for instance, to a young woman who’s suffering from an anxiety disorder and never had a history of bipolar disorder, then she might become hypomanic or manic. Then I put together this with a phenomena related to antidepressants that had been reported in the literature.

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Do Critics of Biological Psychiatry Have an Alternative to a Life of “Whack-A-Mole”?

Mad in America

There is no more important institution in establishment psychiatry than the National Institute of Mental Health (NIMH), and in 2022, psychiatrist Thomas Insel, NIMH director from 2002-2015, stated in his book Healing , The idea of mental illness as a chemical imbalance has now given way to mental illnesses as connectional or brain circuit disorders.

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Cochrane Recommends Antidepressants for Anxiety in a Garbage In, Garbage Out Review

Mad in America

I n early 2025, Cochrane published a seriously flawed review of antidepressants for generalised anxiety disorder. The senior author, Giuseppe Guaiana, said that their research showed that the drugs are “highly effective” at treating generalised anxiety disorder. 2 This is totally false. BMJ 2025;388:r209. 3 Hamilton M.

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Essential Reads: Screening for Anxiety Disorders During Pregnancy and the Postpartum Period

MGH Center for Women's Mental Health

Anxiety symptoms are common during pregnancy and the postpartum period. According to a recent meta-analysis from Fawcett and colleagues, about one out of every five women has at least one type of anxiety disorder during pregnancy or the postpartum period.