Successfully Prescribing MAOIs for Depression
Psychiatric Times
JULY 24, 2025
2,3 MAOIs inhibit MAO in the brain, thereby increasing the intracellular concentrations of serotonin (5HT), norepinephrine (NE), and dopamine (DA), resulting in an absolute increase in extracellular synaptic monoamine concentrations of these 3 major neurotransmitters linked to mood and anxiety disorders. J Affect Disord.
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