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Many people also believe the psychiatric drugs prescribed to treat depression are effective because they correct a verified biological causation for depression, a chemical imbalance in the brain. NIMH and psychiatrists have not always explained depression to be genetic (as “running in the family). A psychiatric textbook (Silverman, C.,
P sychiatry’s serotonin-imbalance theory of depression, long discarded by researchers, was finally flushed down the toilet by psychiatry and the mainstream media in 2022. And psychiatrists’ primary treatments for depression—their so-called “antidepressants”—are now circling the drain. 2) What approach to depression makes sense? Genes and depression?
Joanna Moncrieff, Chemically Imbalanced (2025) E stablishment psychiatry has recently switched the biological cause of mental illness from a chemical imbalance to a brain circuitry defect. Challenging the biological model of depression feels like a game of whack-a-mole: as soon as you put one theory to bed, another one sprouts up.
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