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References 1. Visualizing Novel Therapeutic Targets for Patients with Major Depressive Disorder. After hitting roadblocks and not seeing improvement, Elpidio told attendees these agents helped her feel like “I’m really doing my job.” For more coverage of the Southern California Meeting, visit PsychiatricTimes.com.
References 1. Most of our agents that we talk about as mood stabilizers may be effective in preventing a manic episode or treating mania or mixed states,” Maguire said. Our options are more limited when it comes to bipolar depression, and we do have some agents that are FDA approved specifically for bipolar depression.”
An sNDA for Caplyta as an adjunctive treatment for adults with major depressive disorder (MDD) is also currently under FDA review, submitted back in December 2024. References 1. points (effect size 0.61) in study 501 and 4.5 points (effect size 0.56) vs placebo in study 502. Supplemental new drug application submitted to U.S.
References 1. After the FDA rejection of Lykos Therapeutics’ midomafetamine (MDMA)-assisted psychotherapy tempered excitement for psychedelic therapeutics, 2 this positive data could generate new momentum. News release. June 23, 2025.
Reference Godfrey K, Douglass H, Erritzoe D, et al. The role of GABA, glutamate, and Glx levels in treatment of major depressive disorder: a systematic review and meta-analysis. Reference Shah MR, Jampa A, Kaur M, et al. Transcranial magnetic stimulation for major depressive disorder in pregnancy: a literature review.
Ultimately, what is clinically important in assessing a drug’s risk/benefit for a patient is the serum level using an established reference range with prespecified criteria to create a meaningful and reproducible result. 11 References 1. Despite this, this testing continues to be underutilized in clinical practice for unclear reasons.
References 1. Dr Miller is Medical Director, Brain Health, Exeter, New Hampshire; Editor in Chief, Psychiatric Times ; Staff Psychiatrist, Seacoast Mental Health Center, Exeter; Consulting Psychiatrist, Insight Meditation Society, Barre, Massachusetts. Griffiths K, Won Y, Lee Z, et al. BMC Psychiatry. 2025;25(1):407.
References 1. but in what areas can we improve treatment outcomes and real-world functioning for patients with PTSD? but in what areas can we improve treatment outcomes and real-world functioning for patients with PTSD? 5 key take-aways about PTSD treatment: a closer look at MDMA. Psychiatric Times. August 9, 2024.
References 1. Dr Stahl is an internationally recognized clinician, researcher and teacher in psychiatry with subspecialty expertise in psychopharmacology. He is currently a professor at the University of California, San Diego, and serves as Honorary Fellow in psychiatry department at the University of Cambridge. Stahl SM, Davis RL.
References 1. 3 Unfortunately, approval at the time was not granted. Transcend Therapeutics Receives Breakthrough Therapy Designation for TSND-201 (methylone) for the Treatment of PTSD. Press release. Jul 10, 2025. Accessed July 10, 2025.
References 1. Dr Thordarson is a psychologist and manager of the Outpatient Acute Mental Health Service at the Children’s Hospital of Orange County in California. Dr Rozmid is a psychologist and founder at Clarity CBT & DBT Center and clinical assistant professor at the University of California, Los Angeles. 2024;63(10):956-960.
3 References 1. According to a national survey, an estimated 7 million (11.4%) US children aged 3-17 years have ever been diagnosed with ADHD and approximately half of children with ADHD (53.6%) received ADHD medication. FDA Drug Safety Communication. June 30, 2025.
References 1. Close follow-up and collaboration will help her navigate the therapeutic potential and logistical considerations and improve her care. Dr Feinberg is an associate clinical professor of psychiatry at Montefiore Medical Center, Albert Einstein College of Medicine of Yeshiva University in Bronx, New York. Feinberg S. 2025;42(5).
References 1. Trinh also pointed to recent FDA approvals for acute mania and mixed episodes (including iloperidone, olanzapine, and cariprazine), as well as newer agents for bipolar depression such as lumateperone and lurasidone. Kellogg J, Trinh L, Hanaie J. Conference Proceedings of the Southern California Psychiatry Conference.
References 1. Our world is so instant, and [it is important] to be able to take this time to be with self, be with baby, and just to take that time to enjoy this incredible experience of creating life.” Additional conference coverage can be found at PsychiatricTimes.com. Kuntz L.
Gazzellone, MD, FRCPC Over the past 30 years, the structured definition of medical disease has largely centered on the HDA developed by Jerome Wakefield for mental disorders in 1992. 7 According to the HDA, only dysfunctions that cause significant harm are considered disorders. References 1. Wakefield JC. Psychol Rev.
For example, Robinson points out that US Food and Drug Administration (FDA) categories for pregnancy were phased out around 10 years ago, but are still referred to frequently in practice. References 1. Pregnancy and lactation labeling final rule. Accessed July 1, 2025. Yue M, Kus L, Katta S, et al. J Clin Pharmacol.
References 1. "I'm very excited and very hopeful," Barbee shared. Full coverage of the meeting including expert perspectives of the decision and what it means for clinicians and their patients will be available at PsychiatricTimes.com. Press release. Accessed July 16, 2025.
Lay people posting about mental health can also oversimplify complex psychiatric disorders that mental health professionals obtain years of training to learn to diagnose and treat. 13-15 In addition to self-diagnosing, it has also become more ubiquitous for lay people to use diagnostic terms to refer to acquaintances and public figures.
By definition, technology refers to the application of scientific knowledge to practical purposes, particularly in industry. References 1. When discussing intergenerational gaps, a key question that arises is: Why is technology always at the center of the conversation? Torous J, Bucci S, Bell IH, et al. World Psychiatry.
References NRx Pharmaceuticals, Inc. The FDA has granted Fast Track Designation to NRX-100 for the treatment of acute suicidality, and NRx has also filed a patent application for its novel preservative-free formulation with the US Patent and Trademark Office. Press release. June 23, 2025.
Generally, it refers to compensating for some sort of failure or falling short. Reference 1. There are some psychiatric organizations that use “Redemption” in their names. There is an article about redeeming diagnosis, 1 but not much more that I know of. So that begs the question: What is redemption? 2013:381(9863): 343-5.
References 1. Prodromal features in first-psychotic episodes of major affective and schizoaffective disorders. J Affect Disord. Dr Moukaddam is a professor of psychiatry in the Department of Psychiatry at Baylor College of Medicine and the director of outpatient psychiatry at Harris Health System. 2021;295:1251-1258.
T hese were the exact parameters of my eatingdisorder treatment contract, as defined by my so-called care team when I was 20 years old. I had begun eatingdisorder treatment in May, just five months prior, determined to get an A. Secondly, Jasmine has an eatingdisorder, said the therapist.
References 1. 7-Tesla ultra-high field MRI of the parahippocampal cortex reveals evidence of common neurobiological mechanisms of major depressive disorder and neurotic personality traits. Nießen D, Rajkumar R, Akkoc Altinok DC, et al.
Prevalence refers to the overall occurrence of ADHD in the population at a particular point in time,” Russell Barkley, Ph.D., Incidence refers to the occurrences of newly identified ADHD cases within a specific period. Int J EatDisord. a leading authority on ADHD, explained on his YouTube channel. years, on average.
References 1. Dr Williams is recognized for her contributions to medical education and her dedication to patient care. She currently serves as the department's associate clerkship director and department lead elective officer. Understanding and addressing microaggressions in medicine. Dermatol Clin. 2023;41(2):291-297.
References 1. The original Prescription Drug User Fee Act target action date for Rexulti in combination with sertraline for PTSD was planned for February 8, 2025, and has been postponed until after this week’s advisory committee discussion. July 18, 2025: Meeting of the Psychopharmacologic Drugs Advisory Committee Meeting Announcement.
Individuals with mental disorders have significantly higher rates of other comorbid medical disorders that are under investigation as potential treatment targets for GLP-1 RAs, including binge eatingdisorder, polycystic ovarian syndrome, and noncirrhotic nonalcoholic steatohepatitis. References 1.
Was that so in the story or a veiled reference by the presenter to present day America, I wondered? Zombie Americans? After all, it seems like many of us are now zombie-like, cultishly emerging in a daze from both sides of the political spectrum.
References 1. He is now editing the final book in a 4-volume series on religions and psychiatry for Springer: Islamophobia, anti-Semitism, Christianity, and now The Eastern Religions, and Spirituality. He serves on the Editorial Board of Psychiatric Times. How one Ottawa man came to terms with his father’s Holocaust secrets. Ottawa Citizen.
gustavofrazao/AdobeStock PSYCHIATRIC VIEWS ON THE DAILY NEWS Parts 1 and 2 of the columns considering redemption in psychiatry have found that redemption can seem to apply beyond its usual well-known references in most all religions. To say that in the opposite way, redemption can refer to failure or falling short of all kinds of values.
Notably, the Substance Abuse and Mental Health Services Administration (SAMHSA) statement on these cuts refers to “LGB+ youth services,” 1 excluding the T, Q, and + typical of this acronym, thereby specifically excluding transgender youth and the full spectrum of sexualities. 1 References 1. This is devastating, to say the least.
Last year, it was special for the “Say Hey Kid,” referring to the great baseball early Black star, Willie Mays, who died the day before. References 1. He serves on the Editorial Board of Psychiatric Times. Americans need transformative talks on race. Juneteenth is the space for that. Milwaukee Journal Sentinel. June 3, 2025.
Soon after, in 1932, Jean La Barre coined the word incretin to refer to a ligand that stimulates the endocrine pancreas. References 1. In the late 1800s, Ivan Pavlov, MD, hypothesized that pancreatic secretions in response to an environmental stimulus were mediated by the enteric nervous system. 2025;95:102118. Bayliss WM, Starling EH.
After a tumultuous episode of a hasty suicide attempt, I was promptly referred to a clinical psychology professor at a university in my hometown, who happened to be the senior alumnus of my former therapist. Back then, during my hospitalization at the eatingdisorder clinic, borderline personality disorder was one of those common diagnoses.
References 1. Managing agitation effectively can improve quality of life and delay transitions to more restrictive care settings. The longer we can keep patients at home, surrounded with their family members, the better.” Managing Agitation in Dementia.
Can you refer me to a dietitian or nutritionist? Can therapy help with food-related issues or eatingdisorders? The Role of Food in Therapy for EatingDisorders For individuals dealing with eatingdisorders, therapy often incorporates discussions about food and its role in emotional and physical health.
When Should A Child Be Referred To CAMHS? NHS CAMHS services are generally reserved for moderate to severe mental health difficulties in children and young people.
I have recently grown particularly worried about the large number of young people referred to me with four or five pre-existing diagnoses of chronic conditions, only some of which can be cured. Autism , Tourette syndrome, ADHD, migraines, fibromyalgia, polycystic ovary syndrome, depression, eatingdisorders, anxiety and many more.
1 References 1. reduction in AHI at 26 weeks, with sustained efficacy at 51 weeks. reduction in AHI at 26 weeks, with sustained efficacy at 51 weeks. Their partnership and trust have been instrumental in advancing a new approach to OSA—one that has the possibility of changing how this chronic disease is treated,” concluded Miller.
TriWest Healthcare Alliance commonly referred to as TriWest, is an insurance that is part of the VAs Community Care Network (CCN) that specifically serves veterans. TriWest is the VAs third-party administrator responsible for developing and administering regional networks of high-performing, licensed, and contracted health care providers.
“Dialectical” refers to the issues involved in treating patients with multiple disorders and to the type of thought processes and behavioral styles used in the treatment strategies.
Diagnoses of what are referred to in DSM-5 as neurodevelopmental disorders (ADHD and ASD) are presented as a fundamental truth about who you are. The ‘autistic community’ they are referring to means the online autistic community, with all the problems of social control and conformity which online communities involve.
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