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In summary, researchers have found no serotonin nor any other neurotransmitter association with depression, no neurobiological associations, and no genetic associations. government’s Substance Abuse and MentalHealth Services Administration (SAMHSA) , reported that among American adults, serious suicidal thoughts occurred in 6.6%
Antidepressants, The New York Times informed its readers in 1990 , “work by restoring the balance of neurotransmitter activity in the brain, correcting an abnormal excess or inhibition of the electrochemical signals that control mood, thoughts, appetite, pain and other sensations.” The results , which Rush reported in 2004 , were dispiriting.
As such, the scandal now serves as a historical verdict on the ethics of American psychiatry, and by extension, the National Institute of MentalHealth (NIMH). This ongoing failure can be traced back to the publication of DSM-III in 1980, when American psychiatry adopted a disease model for categorizing and treating mental disorders.
Joanna Moncrieff, Chemically Imbalanced (2025) E stablishment psychiatry has recently switched the biological cause of mental illness from a chemical imbalance to a brain circuitry defect. Establishment psychiatry has shown this same unscientific thinking in its manufacturing of other biological theories of mental illness.
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