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What Is High-Functioning Depression and Are You Missing the Signs?

Center for Integrative Psychiatry

Not all depression looks the same. This is often referred to as high-functioning depression , a form of depression that flies under the radar because those experiencing it can still manage daily responsibilities. But just because someone is functioning doesn’t mean they’re thriving.

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Successfully Prescribing MAOIs for Depression

Psychiatric Times

Exploring the MAOIs The inhibition of isoform monoamine oxidase (MAO)-A generates antidepressant effectiveness because it metabolizes the neurotransmitters associated with depression treatment. References 1. Feinberg S. Understanding and overcoming negative preconceptions about MAOIs. Psychiatric Times. 2025;42(5). Finberg JPM.

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Your beaker, my beaker: Understanding why they’re different

Chipur

Stress capacity: I refer to mine as a beaker. Not right now, the beaker's overflowing." or "Let me pour a little out of the beaker first." Monitoring stress load and capacity is huge. Understanding why each of our beakers are different is crucial.

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The Summertime Blues: Reverse Seasonal Affective Disorder (SAD)

Clear Behavioral Health

Talk therapy or even alternative treatments such as transcranial magnetic stimulation (TMS) could help you get back to enjoying the summertime. If your symptoms don’t seem to be improving, consider a more intensive depression treatment program , like an outpatient or inpatient program for depression at Clear Behavioral Health.

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The Summertime Blues: Reverse Seasonal Affective Disorder (SAD)

Clear Behavioral Health

Talk therapy or even alternative treatments such as transcranial magnetic stimulation (TMS) could help you get back to enjoying the summertime. If your symptoms don’t seem to be improving, consider a more intensive depression treatment program , like an outpatient or inpatient program for depression at Clear Behavioral Health.

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Placebo Effect—Not Antidepressants—Responsible for Depression Improvement

Mad in America

In a study of fluoxetine (Prozac) for adolescents, researchers found that the placebo effect predicted good outcomes, but the actual drug treatment did not. After accounting for “treatment guess” (those who figured out that they were receiving an intervention rather than placebo), the drug was not effective in depression treatment.

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Much of U.S. Healthcare Is Broken: How to Fix It (Chapter 2, Part 2)

Mad in America

S ome of the following studies appeared in my book Antidepressants: Science, Magic or Marketing , 1 and in the next section, I will report on some of the more recent depression treatment outcome studies. even getting on a waiting list for treatment), the severity of their depression lessons in most cases.